HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-(4-aminophenyl)propanoate → Methyl 3-[4-[(4,5-diisopropylfuran-2-carbonyl)amino]phenyl]propionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-(4-aminophenyl)propanoate | HCID 417374 | — |
| Reactant | 4,5-Diisopropylfuran-2-carboxylic acid | HCID 58420514 | — |
| Product | Methyl 3-[4-[(4,5-diisopropylfuran-2-carbonyl)amino]phenyl]propionate | HCID 67394761 | 84% |
Reaction Steps
In the same manner as that of Example 2, 4,5-diisopropylfuran-2-carboxylic acid (90 mg, 0.459 mmol) was condensed with methyl 3-[4-aminophenyl]propionate, and the resultant was purified by silica gel chromatography [benzene-ethyl acetate (14:1)] to obtain methyl 3-[4-[(4,5-diisopropylfuran-2-carbonyl)amino]phenyl]propionate (138 mg, 84%) as colorless needles.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08722730B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-2d2fd1afcc6140cfad96b1741a89c487 |
| Source note | uspto-grants-2014_05 |