反应详情

In the same manner as that of Example 2, 4,5-diisopropylfuran-2-carboxylic acid (86 mg, 0.439 mmol) was condensed with methyl 5-aminopyridine-2-carboxylate, and the resultant was purified by silica gel chromatography (3% methanol-chloroform) to obtain methyl 5-[(4,5-diisopropylfuran-2-carbonyl)amino]pyridine-2-carboxylate (111 mg, 77%) as colorless prisms.

1. customthe resultant was purified by silica gel chromatography (3% methanol-chloroform)