反应详情

In the same manner as that of Example 2, 4,5-diisopropylfuran-2-carboxylic acid (42 mg, 0.214 mmol) was condensed with methyl 5-aminothiophene-2-carboxylate (50 mg, 0.318 mmol), and the resultant was purified by silica gel chromatography (2% methanol-chloroform) to obtain methyl 5-[(4,5-diisopropylfuran-2-carbonyl)amino]thiophene-2-carboxylate (39 mg, 54%) as pale yellow prisms.

1. customthe resultant was purified by silica gel chromatography (2% methanol-chloroform)