Methyl 4-aminobenzoate → HCID 25189527, compound

Participants

Reaction Steps

In the same manner as that of Example 17, 3,5-diisopropylpyrrole-2-carboxylic acid (60 mg, 0.308 mmol) was condensed with methyl 4-aminobenzoate, the reaction mixture was treated in a conventional manner, and then the resultant was purified by silica gel chromatography [hexane-ethyl acetate (3:1)] to obtain the desired condensate (60 mg, 59%) from the high polarity portion, and the starting material substrate acid anhydride (15 mg, 26%) from the low polarity portion.

Provenance & Evidence