Methyl 4-Amino-2-chlorobenzoate → HCID 67395110, compound

Participants

Reaction Steps

In the same manner as that of Example 24, 4,5-diisopropylfuran-2-carboxylic acid (80 mg, 0.408 mmol) and methyl 2-chloro-4-aminobenzoate (136 mg, 0.733 mmol) were condensed, the reaction mixture was treated in a conventional manner, and then the residue was purified by silica gel chromatography [hexane-ethyl acetate (40:1)] and recrystallized to obtain methyl 2-chloro-4-[(4,5-diisopropylfuran-2-carbonyl)amino]benzoate (106 mg, 72%) as colorless prisms.

Provenance & Evidence