HCID 67394461, compound → HCID 67394502, compound

HRID 1023726Notes

Reaction equation

HRID 1023726 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[C:11]([NH:13][C:14]([C:16]2[O:17][C:18]([CH:24]([CH3:26])[CH3:25])=[C:19]([CH:21]([CH3:23])[CH3:22])[CH:20]=2)=[O:15])[CH:10]=[CH:9][C:4]=1[C:5]([O:7]C)=[O:6]>[OH-].[Na+]>[CH3:1][O:2][C:3]1[CH:12]=[C:11]([NH:13][C:14]([C:16]2[O:17][C:18]([CH:24]([CH3:26])[CH3:25])=[C:19]([CH:21]([CH3:22])[CH3:23])[CH:20]=2)=[O:15])[CH:10]=[CH:9][C:4]=1[C:5]([OH:7])=[O:6]

Participants

3

Reactant 1

HCID 67394461HCID 67394461, compound

Product 1

HCID 67394502HCID 67394502, compoundYield 88%

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

The aforementioned ester (65 mg, 0.181 mmol) was hydrolyzed with sodium hydroxide in a conventional manner, and extraction and recrystallization were performed to obtain the title compound (25, 55 mg, 87%) as colorless needles.

Sources & evidence

ORD record
ord-8403de8f5d714b21ad62e3a7eb3b79e0
Source dataset
uspto-grants-2014_05
Patent number
US08722730B2

Reaction notes

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