Ethyl 4-amino-2,6-difluorobenzoate → HCID 67395238, compound

Participants

Reaction Steps

In the same manner as that of Example 24, 4,5-diisopropylfuran-2-carboxylic acid (80 mg, 0.408 mmol) and ethyl 2,6-difluoro-4-aminobenzoate (148 mg, 0.736 mmol) were condensed, the reaction mixture was treated in a conventional manner, and then the residue was purified by silica gel chromatography [n-hexane-ethyl acetate (40:1)] to obtain ethyl 2,6-difluoro-4-[(4,5-diisopropylfuran-2-carbonyl)amino]benzoate (105 mg, 68%).

Provenance & Evidence