Methyl 5-bromofuran-2-carboxylate → HCID 67394175, compound

Participants

Reaction Steps

4,5-Diisopropylfuran-2-carboxamide (55 mg, 0.282 mmol) and methyl 5-bromofuran-2-carboxylate (116 mg, 0.566 mmol) were coupled. The reaction mixture was treated in a conventional manner, and the resultant was purified by silica gel chromatography [hexane-ethyl acetate (9:1)] and recrystallized to obtain methyl 5-[(4,5-diisopropylfuran-2-carbonyl)amino]-2-furancarboxylate (44 mg, 49%) and the collected starting material (26 mg, 47%) as colorless needles.

Provenance & Evidence