Methyl 4-amino-o-anisate → HCID 67394195, compound

Participants

Reaction Steps

In the same manner as that of Example 24, 4,5-diisopropylthiophene-2-carboxylic acid (80 mg, 0.377 mmol) and methyl 2-methoxy-4-aminobenzoate (123 mg, 0.679 mmol) were condensed, the reaction mixture was treated in a conventional manner, and then the residue was purified by silica gel chromatography [n-hexane-ethyl acetate (40:1)] and recrystallized to obtain methyl 2-methoxy-4-[(4,5-diisopropylthiophene-2-carbonyl)amino]benzoate (46 mg, 32%) as colorless prisms.

Provenance & Evidence