HCID 67394195, compound → HCID 67394854, compound

HRID 1023742Notes

Reaction equation

HRID 1023742 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[C:11]([NH:13][C:14]([C:16]2[S:17][C:18]([CH:24]([CH3:26])[CH3:25])=[C:19]([CH:21]([CH3:23])[CH3:22])[CH:20]=2)=[O:15])[CH:10]=[CH:9][C:4]=1[C:5]([O:7]C)=[O:6]>[OH-].[Na+]>[CH3:1][O:2][C:3]1[CH:12]=[C:11]([NH:13][C:14]([C:16]2[S:17][C:18]([CH:24]([CH3:26])[CH3:25])=[C:19]([CH:21]([CH3:22])[CH3:23])[CH:20]=2)=[O:15])[CH:10]=[CH:9][C:4]=1[C:5]([OH:7])=[O:6]

Participants

3

Reactant 1

HCID 67394195HCID 67394195, compound

Product 1

HCID 67394854HCID 67394854, compoundYield 88%

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

The aforementioned ester (42 mg, 0.112 mmol) was hydrolyzed with sodium hydroxide in a conventional manner, and extraction and recrystallization were performed to obtain the title compound (42, 35 mg, 88%) as colorless needles.

Sources & evidence

ORD record
ord-c909dffa775f4a90b74a38833a04edbf
Source dataset
uspto-grants-2014_05
Patent number
US08722730B2

Reaction notes

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