HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 4-Methylthio-3-(trifluoromethyl)phenylboronic acid pinacol ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Pinacol | HCID 6425 | — |
| Reactant | 4-Methylthio-3-(trifluoromethyl)phenylboronic acid | HCID 74891169 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 4-Methylthio-3-(trifluoromethyl)phenylboronic acid pinacol ester | HCID 67277301 | — |
Reaction Steps
The product of step b) (0.25 g) was heated in dioxan (2 ml) with pinacol (2 equiv) for 3 h. The solution was treated with diethyl ether and water. The organic layer was separated, washed with brine, dried (Na2SO4) and concentrated in vacuo. Yield 85 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08722741B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-82e3b650e7ad48f3bc703d0818bb36f2 |
| Source note | uspto-grants-2014_05 |