HCID 59191260, compound → HCID 59191269, compound

HRID 1023903Notes

Reaction equation

HRID 1023903 reaction equation
C[O:2][C:3]1[CH:16]=[C:15]([CH2:17][CH2:18][CH3:19])[CH:14]=[CH:13][C:4]=1[O:5][C:6]1[N:11]=[C:10]([NH2:12])[CH:9]=[CH:8][CH:7]=1>C1CCCCC1.ClCCl>[NH2:12][C:10]1[N:11]=[C:6]([O:5][C:4]2[CH:13]=[CH:14][C:15]([CH2:17][CH2:18][CH3:19])=[CH:16][C:3]=2[OH:2])[CH:7]=[CH:8][CH:9]=1

Participants

3

Reactant 1

HCID 59191260HCID 59191260, compound

Product 1

HCID 59191269HCID 59191269, compoundYield 4.3%

Reagents, catalysts & solvents 1

HCID 21916607Dichloromethane cyclohexaneSolvent

Procedure

According to the procedure of example 5(b) except substituting 2-fluoro-6-(2-methoxy-4-propylphenoxy)pyridine for 6-(2-methoxy-4-propylphenoxy)pyridin-2-amine (125 mg, 0.48 mmol), the title compound (5 mg; 4%) was prepared as a clear oil, after preparative TLC (cyclohexane/dichloromethane).

Sources & evidence

ORD record
ord-cfa443c7d4fd43bfa60d92293c7a1e84
Source dataset
uspto-grants-2014_05
Patent number
US08722746B2

Reaction notes

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