Acetic Acid Mixture with Hydrobromic Acid → HCID 86684167, compound

Participants

Reaction Conditions

Reaction Steps

To an autoclave was charged 124f (800 mg, 2.6 mmol)) and HBr/AcOH (60 mL). It was heated at 150° C. for 18 h. The reaction mixture was concentrated under reduced pressure to give black oil. The oil was recrystallized from methanol (30 mL)/dichloromethane (30 mL)/petroleum ether (90 mL) to 124g as a yellow solid (600 mg, 66%). MS-ESI: [M+H]+ 348.1

Provenance & Evidence