N-Methylbutylamine → HCID 135581815, compound

Participants

Reaction Steps

4.7 A solution of 52 mg of “4f” in 1 ml of THF is added dropwise to a solution of 18.65 mg of N-methylbutylamine and 88.2 μl of N-ethyldiisopropylamine in 2 ml of THF. The mixture is stirred for a further 1 hour and subjected to conventional work-up. For further purification, the residue is chromatographed over an RP18 silica-gel column, giving 18.8 mg of 5-(N-butyl-N-methylaminocarbonyl)-3-(3-methylphenyl)-6-hydroxy-1H-indazole (“A25”)

Provenance & Evidence