4-Pentylbenzoyl chloride → Methyl 3-methyl-2-(4-(4-(4-pentylbenzamido)phenyl)thiazole-2-carboxamido)butanoate

Participants

Reaction Steps

The title compound was synthesized analogous to Example 27, using 4-pentylbenzoyl chloride and intermediate 3. Yield: 56%; 1H NMR (DMSO-d6, 300 MHz): δ 10.32 (s, 1H), 8.84 (d, 1H), 8.37 (s, 1H), 8.12 (d, 2H), 7.91 (bs, 4H), 7.37 (d, 2H), 4.37 (t, 1H), 3.70 (s, 3H), 2.66 (s, 2H), 2.32 (m, 1H), 1.61 (s, 2H), 1.29 (s, 4H), 0.98 (t, 6H), 0.87 (s, 3H).

Provenance & Evidence