HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexylpropionyl chloride → HCID 52935921, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexylpropionyl chloride | HCID 2734098 | — |
| Reactant | Methyl 3-methyl-2-(5-(4-nitrophenyl)thiazole-2-carboxamido)butanoate | HCID 67150324 | — |
| Product | HCID 52935921 | HCID 52935921 | 49% |
Reaction Steps
The title compound was synthesized analogous to Example 27, using 3-cyclohexylpropanoyl chloride and intermediate 2. Yield: 49%; 1H NMR (DMSO-d6, 300 MHz): δ 10.09 (s, 1H), 8.74 (d, 1H), 8.35 (s, 1H), 7.71 (s, 4H), 4.32 (t, 1H), 3.69 (s, 3H), 2.36 (t, 2H), 2.30 (m, 1H), 1.73 (m, 5H), 1.51 (q, 2H), 1.17 (m, 4H), 0.96 (t, 6H), 0.92 (m, 2H); MS (ESI) m/z 472.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08722901B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-161464843cb24b78a05495471b638d63 |
| Source note | uspto-grants-2014_05 |