HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorophenyl Isocyanate → HCID 52933174, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorophenyl Isocyanate | HCID 7693 | — |
| Reactant | Methyl 3-methyl-2-(5-(4-nitrophenyl)thiazole-2-carboxamido)butanoate | HCID 67150324 | — |
| Product | HCID 52933174 | HCID 52933174 | — |
Reaction Steps
The title compound was synthesized analogous to Example 9, using 1-chloro-4-isocyanatobenzene and intermediate 2. 1HNMR (DMSO-d6, 300 MHz): δ 8.991 (s, 1H), 8.897 (s, 1H), 8.737-8.710 (d, 1H), 8.353 (s, 1H), 7.730-7.701 (d, J=8.7 Hz, 2H), 7.583-7.554 (d, J=8.7 Hz, 2H), 7.513-7.484 (d, J=8.7 Hz, 2H), 7.355-7.325 (d, J=9 Hz, 2H), 4.324-4.287 (t, J=7.2, 7.8 Hz, 1H), 3.681 (s, 3H), 2.342-2.242 (m, 1H), 0.965-0.923 (d, J=6.3 Hz, 6H); MS (ESI) m/z 487 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08722901B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-70a0ad99300647a8a5822d1711c2ffd2 |
| Source note | uspto-grants-2014_05 |