HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorophenyl Isocyanate → HCID 52933423, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorophenyl Isocyanate | HCID 7693 | — |
| Reactant | Methyl 3-methyl-2-(4-(4-nitrophenyl)thiazole-2-carboxamido)butanoate | HCID 67150325 | — |
| Product | HCID 52933423 | HCID 52933423 | — |
Reaction Steps
The title compound was synthesized analogous to Example 23, using 4-chlorophenyl isocyanate and intermediate 3. 1HNMR (DMSO-d6, 300 MHz): δ 8.912 (s, 1H), 8.870 (s, 1H), 8.820-8.792 (d, 1H), 8.318 (s, 1H), 8.052-8.024 (d, J=8.4 Hz, 2H), 7.590-7.561 (d, J=8.7 Hz, 2H), 7.521-7.492 (d, J=8.7 Hz, 2H), 7.356-7.326 (d, J=9 Hz, 2H), 4.395-4.343 (t, J=7.8 Hz, 1H), 3.700 (s, 3H), 2.319-2.273 (m, 1H), 1.000-0.953 (t, J=6.9, 7.2 Hz, 6H); MS (ESI) m/z 485 (M−H), 487 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08722901B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-da59366f13484356b7623ede2c475c90 |
| Source note | uspto-grants-2014_05 |