HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 1-chloro-3-isocyanato- → HCID 52933675, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 1-chloro-3-isocyanato- | HCID 17968 | — |
| Reactant | Methyl 3-methyl-2-(4-(4-nitrophenyl)thiazole-2-carboxamido)butanoate | HCID 67150325 | — |
| Product | HCID 52933675 | HCID 52933675 | — |
Reaction Steps
The title compound was synthesized analogous to Example 23, using 3-chlorophenyl isocyanate and intermediate 3. 1HNMR (DMSO-d6, 300 MHz): δ 8.959 (s, 1H), 8.940 (s, 1H), 8.826-8.798 (d, J=8.4 Hz, 1H), 8.325 (s, 1H), 8.058-8.030 (d, J=8.4 Hz, 2H), 7.734 (s, 1H), 7.596-7.567 (d, J=8.7 Hz, 2H), 7.318-7.294 (m, 2H), 7.046-7.023 (m, 1H), 4.395-4.343 (t, J=7.8 Hz, 1H), 3.700 (s, 3H), 2.320-2.274 (m, 1H), 1.001-0.953 (t, J=6.9, 7.5 Hz, 6H); MS (ESI) m/z 485 (M−H), 487 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08722901B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-0fa5e1a001614cd4b02bc260e4b484b4 |
| Source note | uspto-grants-2014_05 |