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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1024576Generated: October 29, 2026

6-chloro-3-(2-ethoxy-3,4-dioxo-cyclobut-1-enylamino)-2-hydroxy-N-methoxy-N-methyl-benzenesulfonamide → 3-(2-Ethoxy-3,4-dioxocyclobut-1-enylamino)-N-ethyl-2-hydroxy-N-methoxy benzenesulfonamide

https://huagongshe.com/reaction/1024576

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-chloro-3-(2-ethoxy-3,4-dioxo-cyclobut-1-enylamino)-2-hydroxy-N-methoxy-N-methyl-benzenesulfonamideHCID 56844293—
Reactant3-Amino-N-ethyl-2-hydroxy-N-methoxybenzenesulfonamideHCID 86638640—
Product3-(2-Ethoxy-3,4-dioxocyclobut-1-enylamino)-N-ethyl-2-hydroxy-N-methoxy benzenesulfonamideHCID 86638641—

Reaction Steps

This compound was prepared analogously to 6-Chloro-3-(2-ethoxy-3,4-dioxo-cyclobut-1-enylamino)-2-hydroxy-N-methoxy-N-methyl-benzenesulfonamide (Intermediate A step 3) by replacing 3-amino-6-chloro-2-hydroxy-N-methoxy-N-methyl-benzenesulfonamide with 3-amino-N-ethyl-2-hydroxy-N-methoxybenzenesulfonamide (step 1). [M+H]+ 371

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08722925B2
Source datasetuspto-grants-2014_05
ORD IDord-0b4b1db98636470f88b5841ee117551f
Source noteuspto-grants-2014_05