HCID 12826362, compound → HCID 86638642, compound

HRID 1024577Notes

Reaction equation

HRID 1024577 reaction equation
[N:1]1[CH:6]=[CH:5][N:4]=[CH:3][C:2]=1[CH:7](O)[CH2:8][CH3:9].[N:11](C([C@H]1CCCO1)CC)=[N+:12]=[N-:13]>>[N:11]([CH:7]([C:2]1[CH:3]=[N:4][CH:5]=[CH:6][N:1]=1)[CH2:8][CH3:9])=[N+:12]=[N-:13]

Participants

3

Reactant 2

HCID 12826362HCID 12826362, compoundHCID 86638632HCID 86638632, compound

Product 1

HCID 86638642HCID 86638642, compound

Procedure

The title compound is prepared from 1-(pyrazin-2-yl)propan-1-ol (prepared according to the procedure of ‘Some reactions of mono substituted pyrazine monoxides’ Journal of Heterocyclic Chemistry (1982), 19(5), 1061-7, Compound 18) analogously to (2R)-2-(1-azidopropyl)tetrahydrofuran (Intermediate DA, step 4).

Workup

  1. customprepared

Sources & evidence

ORD record
ord-abfc8cea7d5945b587c4849ddc63463c
Source dataset
uspto-grants-2014_05
Patent number
US08722925B2

Reaction notes

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