HCID 66818891, compound → HCID 66818531, compound

Participants

Reaction Steps

10% Pd/carbon (0.24 g) was added under hydrogen atmosphere (balloon pressure) to a stirred solution of 2,6-Bis(4-Cyano phenoxy)-3-nitro pyridine (1.20 g, 3.35 mmol) in 20 ml of methanol:ethyl acetate (1:1) at ambient temperature and the reaction mixture was stirred for 1 h. The reaction mixture was filtered through celite, washed with 20 ml of ethyl acetate and concentrated under reduced pressure. Water was added to the residual mixture and it was extracted with ethyl acetate. Ethyl acetate layer was washed with water followed by brine. The organic layer was dried over sodium sulphate to afford 0.95 g of the title product which was used for the next step without further purification. 1H NMR (DMSO-d6): δ 5.32 (2H, brs), 6.82 (1H, d), 7.15 (1H, d), 7.22 (2H, d), 7.34 (2H, d), 7.80 (4H, m).

Provenance & Evidence