HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-aminopropanoate → 3-{[2,6-Bis-(4-cyano-phenoxy)-pyridine-3-carbonyl]-amino}-propionicacid Ethyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-aminopropanoate | HCID 419889 | — |
| Reactant | 2,6-Bis(4-cyanophenoxy)-nicotinic acid | HCID 67605998 | — |
| Product | 3-{[2,6-Bis-(4-cyano-phenoxy)-pyridine-3-carbonyl]-amino}-propionicacid Ethyl Ester | HCID 66818106 | 77.1% |
Reaction Steps
Following the procedure of Example 5(c) 2,6-bis(4-Cyano phenoxy)-nicotinic acid 0.5 g (1.42 mmol) and 3-amino-propionic acid ethyl ester (0.166 g, 1.42 mmol) were used to afford 0.5 g of the required product. Percentage purity (LCMS): 30.7%, (M+1)=456.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08722930B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-f3c56f16b175444ea4a2013e5e546a61 |
| Source note | uspto-grants-2014_05 |