HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Aminoethyl)piperidine, 4-BOC protected → HCID 66818437, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Aminoethyl)piperidine, 4-BOC protected | HCID 1501849 | — |
| Reactant | HCID 66818840 | HCID 66818840 | — |
| Product | HCID 66818437 | HCID 66818437 | 78.2% |
Reaction Steps
6-(4-cyano phenoxy)-2-(4-fluoro phenoxy)nicotinic acid (0.2 g, 0.57 mmol) and (2-piperidin-4-yl-ethyl)-carbamic acid tert-butyl ester (0.13 g, 0.57 mmol) were coupled using the procedure of Example 5(c) to afford 0.25 g of the required product. Percentage purity: LCMS (−ve mode): 67.5%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08722930B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-64c4fcdc125845e7b337ad2e75bfafc6 |
| Source note | uspto-grants-2014_05 |