4-Fluorobenzenesulfonyl chloride → HCID 66818562, compound

HRID 1024709Notes

Reaction equation

HRID 1024709 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([S:8](Cl)(=[O:10])=[O:9])=[CH:4][CH:3]=1.[C:12]([C:14]1[CH:36]=[CH:35][C:17]([O:18][C:19]2[CH:24]=[C:23]([O:25][C:26]3[CH:31]=[CH:30][C:29]([C:32]#[N:33])=[CH:28][CH:27]=3)[CH:22]=[CH:21][C:20]=2[NH2:34])=[CH:16][CH:15]=1)#[N:13]>>[C:12]([C:14]1[CH:36]=[CH:35][C:17]([O:18][C:19]2[CH:24]=[C:23]([O:25][C:26]3[CH:31]=[CH:30][C:29]([C:32]#[N:33])=[CH:28][CH:27]=3)[CH:22]=[CH:21][C:20]=2[NH:34][S:8]([C:5]2[CH:6]=[CH:7][C:2]([F:1])=[CH:3][CH:4]=2)(=[O:10])=[O:9])=[CH:16][CH:15]=1)#[N:13]

Participants

3

Reactant 2

HCID 95884-Fluorobenzenesulfonyl chlorideHCID 66820986HCID 66820986, compound

Product 1

HCID 66818562HCID 66818562, compoundYield 68.7%

Procedure

4-Fluorobenzene sulfonyl chloride (0.126 g, 0.65 mmol) was added to a stirred solution of 1,5-bis-(4-cyano-phenoxy)-2-aminobenzene (0.175 g, 0.54 mmol) along with other reagents as mentioned in Example 20(c) to afford 0.18 g of the required product. 1H NMR (DMSO-d6): δ 6.86 (1H, brs), 6.95 (3H, m), 7.26 (2H, d), 7.34 (1H, d), 7.54 (3H, t), 7.82 (2H, d), 7.95 (2H, d), 7.95 (2H, m).

Sources & evidence

ORD record
ord-7724acaacda144eeb869cd364cf6a088
Source dataset
uspto-grants-2014_05
Patent number
US08722930B2

Reaction notes

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