Cis tert-Butyl 4-aminocyclohexylcarbamate → HCID 66818715, compound

Participants

Reaction Steps

Following the procedure of Example 5(c) 3,5-bis-(5-cyano-pyridin-2-yloxy)-benzoic acid 0.35 g (0.97 mmol) and (4-amino-cyclohexyl)-carbamic acid tert-butyl ester (0.2 g, 0.97 mmol) were used to afford 0.4 g. of the required product. 1H NMR (DMSO-d6): δ 1.47 (9H, s), 1.72 (5H, m), 1.82 (3H, m), 3.20 (1H, m), 3.72 (1H, m), 6.74 (1H, m), 7.18 (1H, d), 7.32 (1H, s), 7.50 (1H, brs), 7.59 (1H, s), 8.08 (1H, brs), 8.30 (2H, dd), 8.39 (1H, dd), 8.67 (2H, d).

Provenance & Evidence