tert-Butyl N-(2-bromoethyl)carbamate → HCID 66818548, compound

Participants

Reaction Steps

Following the procedure of Example 11(e) 4-[3,5-bis-(4-cyano-phenoxy)-benzoyl]-piperazine 0.35 g (0.82 mmol) and (2-bromo-ethyl)-carbamic acid tert-butyl ester (0.183 g, 0.82 mmol) were used to afford 0.4 g of the required product. 1H NMR (DMSO-d6): 1.39 (9H, s), 2.28 (6H, m), 3.04 (2H, m), 3.54 (2H, m), 6.65 (1H, brs), 6.98 (2H, d), 7.05 (1H, t), 7.25 (4H, d), 7.88 (4H, d).

Provenance & Evidence