Diisobutylamine → HCID 66818655, compound

HRID 1024724Notes

Reaction equation

HRID 1024724 reaction equation
[C:1]([C:3]1[CH:27]=[CH:26][C:6]([O:7][C:8]2[CH:9]=[C:10]([CH:14]=[C:15]([O:17][C:18]3[CH:23]=[CH:22][C:21]([C:24]#[N:25])=[CH:20][CH:19]=3)[CH:16]=2)[C:11]([OH:13])=O)=[CH:5][CH:4]=1)#[N:2].[CH2:28]([NH:32][CH2:33][CH:34]([CH3:36])[CH3:35])[CH:29]([CH3:31])[CH3:30]>>[C:1]([C:3]1[CH:27]=[CH:26][C:6]([O:7][C:8]2[CH:9]=[C:10]([CH:14]=[C:15]([O:17][C:18]3[CH:23]=[CH:22][C:21]([C:24]#[N:25])=[CH:20][CH:19]=3)[CH:16]=2)[C:11]([N:32]([CH2:33][CH:34]([CH3:36])[CH3:35])[CH2:28][CH:29]([CH3:31])[CH3:30])=[O:13])=[CH:5][CH:4]=1)#[N:2]

Participants

3

Reactant 2

HCID 8085DiisobutylamineHCID 66818818HCID 66818818, compound

Product 1

HCID 66818655HCID 66818655, compoundYield 70.7%

Procedure

Following the procedure of Example 5(c) 3,5-bis-(4-cyano-phenoxy)-benzoic acid 0.8 g (2.24 mmol) and diisobutyl-amine (0.29 g, 2.24 mmol) were used to afford 0.74 g of the required product. 1H NMR (DMSO-d6): δ 0.72 (6H, d), 0.88 (6H, d), 1.82 (1H, m), 2.00 (1H, m), 3.06 (2H, d), 3.24 (2H, d), 6.98 (2H, d), 7.04 (1H, t), 7.22 (4H, d), 7.89 (4H, d).

Sources & evidence

ORD record
ord-13795d46150045679deab1fd4805e893
Source dataset
uspto-grants-2014_05
Patent number
US08722930B2

Reaction notes

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