Cis tert-Butyl 4-aminocyclohexylcarbamate → HCID 66818751, compound

Participants

Reaction Steps

Following the procedure of Example 5(c) 3-(3-cyano benzyloxy)-5-(4-cyano phenoxy)benzoic acid 0.46 g (1.24 mmol) and (4-amino-cyclohexyl)-carbamic acid tert-butyl ester (0.265 g, 1.24 mmol) were used to afford 0.52 g of the required product. 1H NMR (DMSO-d6): δ 1.25 (4H, m), 1.40 (9H, s), 1.8 (4H, m), 3.2 (1H, m), 3.7 (1H, m), 5.25 (2H, s), 6.74 (1H, d), 7.02 (1H, s), 7.32 (2H, d), 7.22 (1H, s), 7.44 (1H, s), 7.64 (1H, m), 7.84 (4H, m), 7.95 (1H, s), 8.3 (1H, d).

Provenance & Evidence