Ethyl 4-(bromomethyl)benzoate → HCID 66818755, compound

Participants

Reaction Steps

Using 0.52 g (1.31 mmol) of 4-[3-(4-cyano phenoxy)-5-hydroxy benzoyl]-piperazine-1-carboxylic acid ethyl ester and 4-bromomethyl-benzoic acid ethyl ester (0.318 g, 1.31 mmol) and following the procedure of Example 42(b) affored 0.61 g of the required product. Percentage purity (LCMS): 60.0% (M+1)=557.2+1.

Provenance & Evidence