Cis tert-Butyl 4-aminocyclohexylcarbamate → HCID 66818239, compound

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Reaction Steps

Following the procedure of Example 5(c) 3-(2-chloro-4-cyano phenoxy)-5-(4-cyano phenoxy)benzoic acid 1.0 g (2.55 mmol) and (4-amino-cyclohexyl)-carbamic acid tert-butyl ester (0.54 g, 2.55 mmol) were used to afford 1.2 g of the required product. 1H NMR (DMSO-d6): δ 1.24 (4H, m), 1.38 (9H, s), 1.8 (4H, m), 3.2 (1H, m), 3.68 (1H, m), 6.76 (1H, d), 7.22 (4H, m), 7.5 (2H, s), 7.88 (3H, m), 8.26 (1H, d), 8.38 (1H, d).

Provenance & Evidence