Ethyl 4-aminocyclohexanecarboxylate → HCID 66818518, compound

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Reaction Steps

Following the procedure of Example 9(e) 3,5-bis-(4-cyano-phenoxy)-benzoic acid 1.0 g (2.6 mmol) and 4-amino-cyclohexanecarboxylic acid ethyl ester (0.48 g, 2.6 mmol) were used to afford 0.5 g of the required product. 1H NMR (DMSO-d6): δ 1.34 (5H, m), 1.41 (5H, m), 1.92 (4H, m), 2.1 (1H, t), 3.81 (1H, m), 4.12 (2H, q), 7.04 (4H, dd), 7.51 (2H, s), 7.89 (3H, d), 8.41 (1H, d). Percentage purity (HPLC): 89.3%.

Provenance & Evidence