Cyclohexanemethylamine → HCID 66818543, compound

HRID 1024817Notes

Reaction equation

[C:1]([C:3]1[CH:27]=[CH:26][C:6]([O:7][C:8]2[CH:9]=[C:10]([CH:14]=[C:15]([O:17][C:18]3[CH:23]=[CH:22][C:21]([C:24]#[N:25])=[CH:20][CH:19]=3)[CH:16]=2)[C:11]([OH:13])=O)=[CH:5][CH:4]=1)#[N:2].[CH:28]1([CH2:34][NH2:35])[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]1>>[C:1]([C:3]1[CH:27]=[CH:26][C:6]([O:7][C:8]2[CH:9]=[C:10]([CH:14]=[C:15]([O:17][C:18]3[CH:19]=[CH:20][C:21]([C:24]#[N:25])=[CH:22][CH:23]=3)[CH:16]=2)[C:11]([NH:35][CH2:34][CH:28]2[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]2)=[O:13])=[CH:5][CH:4]=1)#[N:2]

Participants

Reactant 2

HCID 76688Cyclohexanemethylamine

HCID 66818818HCID 66818818, compound

Product 1

HCID 66818543HCID 66818543, compoundYield 105.5%

Procedure

Following the procedure of Example 9(e) 3,5-bis-(4-cyano-phenoxy)-benzoic acid 0.5 g (1.26 mmol) and cyclohexylmethylamine (0.143 g, 1.26 mmol) were used to afford 0.60 g of the required product. Percentage purity (LCMS): 97.6%, (M+1)=451.1+1.

Sources & evidence

ORD record: ord-2cbafd409e574cccb7c380de4f7d0717
Source dataset: uspto-grants-2014_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08722930B2

Reaction notes

Loading…