5-Chloro-2-propyl-[1,8]naphthyridine → [3-(4-Bromo-benzyloxy)-5-chloro-phenyl]-(7-propyl-[1,8]naphthyridin-4-yl)-amine

HRID 102483Notes

Reaction equation

HRID 102483 reaction equation
[Br:15][c:16]1[cH:17][cH:18][c:19]([CH2:20][O:21][c:22]2[cH:23][c:24]([NH2:29])[cH:25][c:26]([Cl:28])[cH:27]2)[cH:30][cH:31]1.[Cl:1][c:2]1[c:3]2[cH:4][cH:5][c:6]([CH2:12][CH2:13][CH3:14])[n:7][c:8]2[n:9][cH:10][cH:11]1>>[c:2]1([NH:29][c:24]2[cH:23][c:22]([O:21][CH2:20][c:19]3[cH:18][cH:17][c:16]([Br:15])[cH:31][cH:30]3)[cH:27][c:26]([Cl:28])[cH:25]2)[c:3]2[cH:4][cH:5][c:6]([CH2:12][CH2:13][CH3:14])[n:7][c:8]2[n:9][cH:10][cH:11]1

Participants

3

Reactant 2

HCID 441401765-Chloro-2-propyl-[1,8]naphthyridineHCID 684611983-(4-Bromo-benzyloxy)-5-chloro-phenylamine

Product 1

HCID 68460460[3-(4-Bromo-benzyloxy)-5-chloro-phenyl]-(7-propyl-[1,8]naphthyridin-4-yl)-amine

Sources & evidence

ORD record
ord-1b1a6ba9ac9b40e9a1c3899cf40dfb29
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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