3-[4-(1-Amino-cyclobutyl)-phenyl]-6-fluoro-2-phenyl-chromen-4-one → 3-[4-(1-Amino-cyclobutyl)-phenyl]-7-(2-methoxy-ethyl)-2-phenyl-7H-pyrano[2,3-c]pyridine-4,8-dione

HRID 102498Notes

Reaction equation

HRID 102498 reaction equation
[C:30]([O:31][C:32](=[O:33])[NH:36][C:37]1([c:41]2[cH:42][cH:43][c:44](-[c:47]3[c:48](=[O:68])[c:49]4[c:50]([c:51](=[O:59])[n:52]([CH2:55][CH2:56][O:57][CH3:58])[cH:53][cH:54]4)[o:60][c:61]3-[c:62]3[cH:63][cH:64][cH:65][cH:66][cH:67]3)[cH:45][cH:46]2)[CH2:38][CH2:39][CH2:40]1)([CH3:34])([CH3:35])[CH3:69].[NH2:1][C:2]1([c:3]2[cH:4][cH:5][c:6](-[c:7]3[c:8](=[O:9])[c:10]4[c:11]([cH:12][cH:13][c:14]([F:15])[cH:16]4)[o:17][c:18]3-[c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[cH:25][cH:26]2)[CH2:27][CH2:28][CH2:29]1>>[NH2:36][C:37]1([c:41]2[cH:42][cH:43][c:44](-[c:47]3[c:48](=[O:68])[c:49]4[c:50]([c:51](=[O:59])[n:52]([CH2:55][CH2:56][O:57][CH3:58])[cH:53][cH:54]4)[o:60][c:61]3-[c:62]3[cH:63][cH:64][cH:65][cH:66][cH:67]3)[cH:45][cH:46]2)[CH2:38][CH2:39][CH2:40]1

Participants

3

Reactant 2

HCID 510305983-[4-(1-Amino-cyclobutyl)-phenyl]-6-fluoro-2-phenyl-chromen-4-oneHCID 86671020(1-{4-[7-(2-methoxy-ethyl)-4,8-dioxo-2-phenyl-7,8-dihydro-4H-pyrano[2,3-c]pyridin-3-yl]-phenyl}-cyclobutyl)-carbamic acid tert-butyl ester

Product 1

HCID 510295893-[4-(1-Amino-cyclobutyl)-phenyl]-7-(2-methoxy-ethyl)-2-phenyl-7H-pyrano[2,3-c]pyridine-4,8-dione

Sources & evidence

ORD record
ord-7b70efaf47244e908670d98a81162d74
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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