Dimethylformamide → HCID 86646198, compound

Participants

Reaction Conditions

Reaction Steps

To chloro-bis[4-(12-docosoxydodecyloxy)phenyl]methane (80.9 mg, 66.3 mmol) were added DMF (3 ml), chloroform (1 ml), and sodium azide (40 mg, 621 μmol) and the mixture was stirred at 80° C. for 6 hours. Sodium azide (40.4 mg, 621 μmol) was added, and the mixture was stirred at 90° C. for 1.5 hours. The mixture was cooled to room temperature. Chloroform (2 ml) was added, and the mixture was washed with purified water (3 ml)×3 for partitioning, and the organic layer was evaporated under reduced pressure. The residue was crystallized from acetonitrile to give azido-bis[4-(12-docosoxydodecyloxy)phenyl]methane (72.0 mg, 58.7 μmol, 89%).

Provenance & Evidence