Trifluoroacetic acid → HCID 59275351, compound

Participants

Reaction Steps

2-(4-Fluorophenyl)-5-(5-(isobutylcarbamoyl)-2-(piperidin-3-ylmethoxy)phenyl)-N-methyl benzofuran-3-carboxamide, TFA. 1H NMR (400 MHz, THF-d8) δ ppm 0.93 (d, J=6.78 Hz, 6 H), 1.40-1.57 (m, 1 H), 1.75-2.00 (m, 4 H), 2.33 (br. s., 1 H), 2.80-3.00 (m, 5 H), 3.18 (t, J=6.40 Hz, 2 H), 3.32 (d, J=12.05 Hz, 1 H), 3.45 (d, J=10.79 Hz, 1 H), 3.90-4.12 (m, 2 H), 7.03 (d, J=8.53 Hz, 1 H), 7.22 (t, J=8.78 Hz, 2 H), 7.47 (dd, J=8.53, 1.51 Hz, 1 H), 7.58 (d, J=8.53 Hz, 1 H), 7.71 (t, J=5.65 Hz, 1 H), 7.75-7.86 (m, 2 H), 7.92 (s, 2 H), 8.01 (dd, J=8.78, 5.52 Hz, 2 H). LCMS m/z 558.20 (M+H), Rt 1.595 min. HPLC Rt 6.443 min. (Sunfire C18), 99.2% purity and 10.418 min. (XBridge Phenyl C18), 99.2% purity.

Provenance & Evidence