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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1025302Generated: October 25, 2026

tert-butyl N-(1-hydroxy-2-methylpropan-2-yl)carbamate → 3-amino-N-cyclopropyl-2-hydroxy-3-methylbutanamide

https://huagongshe.com/reaction/1025302

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl N-(1-hydroxy-2-methylpropan-2-yl)carbamateHCID 14578673—
Reactant(2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochlorideHCID 86762404—
Product3-amino-N-cyclopropyl-2-hydroxy-3-methylbutanamideHCID 57562093—

Reaction Steps

The title compound was prepared in analogy to (2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochloride, Representative Procedure A, starting with tert-butyl 1-hydroxy-2-methylpropan-2-ylcarbamate in the second step (A2).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729061B2
Source datasetuspto-grants-2014_05
ORD IDord-9b68c9b4801649729f8cf86cc2f551ea
Source noteuspto-grants-2014_05