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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1025303Generated: October 25, 2026

(1-Formylcyclopropyl)carbamic acid tert-butyl ester → 2-(1-aminocyclopropyl)-N-cyclopropyl-2-hydroxyacetamide

https://huagongshe.com/reaction/1025303

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1-Formylcyclopropyl)carbamic acid tert-butyl esterHCID 10352385—
Reactant(2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochlorideHCID 86762404—
Product2-(1-aminocyclopropyl)-N-cyclopropyl-2-hydroxyacetamideHCID 57562096—

Reaction Steps

The title compound was prepared in analogy to (2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochloride, Representative Procedure A, starting with tert-butyl 1-formylcyclopropylcarbamate in the third step (A3).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729061B2
Source datasetuspto-grants-2014_05
ORD IDord-7cab54402649426cb55b94ad5a505f70
Source noteuspto-grants-2014_05