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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1025308Generated: October 27, 2026

Butyl isocyanide → (2S,3S)-3-Amino-N-butyl-2-hydroxyhexanamide dihydrochloride

https://huagongshe.com/reaction/1025308

Reaction equation

Participants

RoleNameHCIDCharge
ReactantButyl isocyanideHCID 76008—
Reactant(2S)-2-aminopentan-1-olHCID 6951248—
Reactant(2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochlorideHCID 86762404—
Product(2S,3S)-3-Amino-N-butyl-2-hydroxyhexanamide dihydrochlorideHCID 86762413—

Reaction Steps

The title compound was prepared in analogy to (2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochloride, Representative Procedure A, using (S)-2-aminopentan-1-ol in the first step (A1), and 1-isocyanobutane in the third step (A3).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729061B2
Source datasetuspto-grants-2014_05
ORD IDord-97f5da1cfd2547dfbd322d83831b88f6
Source noteuspto-grants-2014_05