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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1025311Generated: October 26, 2026

2-Pentyl isocyanide → (2S,3S)-3-Amino-2-hydroxy-N-(pentan-2-yl)hexanamide dihydrochloride

https://huagongshe.com/reaction/1025311

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Pentyl isocyanideHCID 4084558—
Reactant(2S)-2-aminopentan-1-olHCID 6951248—
Reactant(2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochlorideHCID 86762404—
Product(2S,3S)-3-Amino-2-hydroxy-N-(pentan-2-yl)hexanamide dihydrochlorideHCID 86762419—

Reaction Steps

The title compound was prepared in analogy to (2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochloride, Representative Procedure A, starting with (S)-2-aminopentan-1-ol in the first step (A1), and using 2-isocyanopentane in the third step (A3).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729061B2
Source datasetuspto-grants-2014_05
ORD IDord-b299ebf622b94572b576b92d41094a87
Source noteuspto-grants-2014_05