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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1025313Generated: October 31, 2026

Isopropylamine → (2S,3S)-3-Amino-2-hydroxy-N-isopropylhexanamide

https://huagongshe.com/reaction/1025313

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsopropylamineHCID 6363—
ReactantL-NorvalineHCID 65098—
Reactant(2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamideHCID 57872123—
Product(2S,3S)-3-Amino-2-hydroxy-N-isopropylhexanamideHCID 86762422—

Reaction Steps

The title compound was prepared in analogy to (2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide, Representative Procedure B, using (S)-2-aminopentanoic acid in the first step (step B1), and isopropylamine in the seventh step (step B7).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729061B2
Source datasetuspto-grants-2014_05
ORD IDord-a1c0d75f00614a23adcbe92ecc10694a
Source noteuspto-grants-2014_05