HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Norvaline → (2S,3S)-3-Amino-N-cyclopropyl-2-hydroxy-N-methylhexanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Norvaline | HCID 65098 | — |
| Reactant | N-Methylcyclopropanamine | HCID 11029756 | — |
| Reactant | (2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide | HCID 57872123 | — |
| Product | (2S,3S)-3-Amino-N-cyclopropyl-2-hydroxy-N-methylhexanamide | HCID 86762427 | — |
Reaction Steps
The title compound was prepared in analogy to (2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide, Representative Procedure B, using (S)-2-aminopentanoic acid in the first step (step B1), and N-methylcyclopropanamine in the seventh step (step B7).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08729061B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-d3de8b7588684163bc7b4824cf798d33 |
| Source note | uspto-grants-2014_05 |