Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1025381Generated: November 2, 2026

Hydrochloric Acid → HCID 71268826, compound

https://huagongshe.com/reaction/1025381

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 71268944HCID 71268944—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 71268826HCID 71268826—

Reaction Steps

Tert-butyl 4-(4-(2-(4-(methoxycarbonyl)phenyl)-5-oxo-5,6-dihydropyrimido[4,5-d]pyridazin-4-ylamino)benzyl)piperazine-1-carboxylate (0.1 g, 0.175 mmol) was dissolved in dioxane.HCl (5 mL) and stirred at room temperature for 1.5 hours. The solid obtained was filtered and the residue washed with EtOAc and dried to give the desired product (40 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729079B2
Source datasetuspto-grants-2014_05
ORD IDord-5e3464f08dde481295e64c21f209fb37
Source noteuspto-grants-2014_05