Hydrogen chloride-ethyl acetate → HCID 178501217, compound

Participants

Reaction Steps

To a mixture of 1.8 g of methyl trans-4-[(tert-butoxycarbonyl)(isopropyl)amino]cyclohexane carboxylate and 20 mL of ethyl acetate were added 20 mL of a 4.0 M hydrogen chloride/ethyl acetate solution, followed by stirring at room temperature for 3 hours. The reaction mixture was concentrated under reduced pressure to obtain 1.18 g of methyl trans-4-(isopropylamino)cyclohexane carboxylate hydrochloride as a colorless solid.

Provenance & Evidence