HRID1025506

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1

HCID4642098

tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydropyridine-1(2H)-carboxylate

C16H28BNO4

结构：CCCc1cnc(N2CCC(O)(C3Cc4cc(C5=CCN(C(=O)OC(C)(C)C)CC5)cc(F)c4O3)CC2)nc1

HCID67468836

未命名化合物

结构：CCCS(=O)(=O)N1CCC(C2Cc3cc(Br)ccc3O2)CC1

HCID67468933

未命名化合物

PRODUCTS

生成物

结构：CCCS(=O)(=O)N1CCC(C2Cc3cc(C4=CCN(C(=O)OC(C)(C)C)CC4)ccc3O2)CC1

HCID68211536

未命名化合物

PROCEDURE

实验过程

Compound 10B was prepared from Compound 10A and tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydropyridine-1(2H)-carboxylate in a similar manner to the procedure described for Compound 1I in Example 1.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-0a4e419d49c84caa94e00a74c21f440e
来源数据集: uspto-grants-2014_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08729084B2
来源说明: uspto-grants-2014_05

反应 SMILES

Br[C:2]1[CH:3]=[CH:4][C:5]2[O:9][CH:8]([CH:10]3[CH2:15][CH2:14][N:13]([S:16]([CH2:19][CH2:20][CH3:21])(=[O:18])=[O:17])[CH2:12][CH2:11]3)[CH2:7][C:6]=2[CH:22]=1.CC1(C)C(C)(C)OB([C:31]2[CH2:36][CH2:35][N:34]([C:37]([O:39][C:40]([CH3:43])([CH3:42])[CH3:41])=[O:38])[CH2:33][CH:32]=2)O1.FC1C2OC(C3(O)CCN(C4N=CC(CCC)=CN=4)CC3)CC=2C=C(C2CCN(C(OC(C)(C)C)=O)CC=2)C=1>>[CH2:19]([S:16]([N:13]1[CH2:14][CH2:15][CH:10]([CH:8]2[CH2:7][C:6]3[CH:22]=[C:2]([C:31]4[CH2:36][CH2:35][N:34]([C:37]([O:39][C:40]([CH3:43])([CH3:42])[CH3:41])=[O:38])[CH2:33][CH:32]=4)[CH:3]=[CH:4][C:5]=3[O:9]2)[CH2:11][CH2:12]1)(=[O:18])=[O:17])[CH2:20][CH3:21]