Trifluoroacetic acid → 4-(2-(1-(Propylsulfonyl)piperidin-4-yl)-2,3-dihydrobenzofuran-5-yl)-1,2,3,6-tetrahydropyridine

Participants

Role	Name	HCID	Charge
Reactant	Trifluoroacetic acid	HCID 6422	—
Reactant	4-(7-Fluoro-5-(1,2,3,6-tetrahydropyridin-4-yl)-2,3-dihydrobenzofuran-2-yl)-1-(5-propylpyrimidin-2-yl)piperidin-4-ol	HCID 67465776	—
Reactant	tert-Butyl 4-(2-(1-(propylsulfonyl)piperidin-4-yl)-2,3-dihydrobenzofuran-5-yl)-5,6-dihydropyridine-1(2H)-carboxylate	HCID 68211536	—
Product	4-(2-(1-(Propylsulfonyl)piperidin-4-yl)-2,3-dihydrobenzofuran-5-yl)-1,2,3,6-tetrahydropyridine	HCID 67468845	—

Compound 10C was prepared from Compound 10B and TFA in a similar manner to the procedure described for Compound 1J in Example 1.