Thionyl Chloride → HCID 15015183, compound

Participants

Reaction Steps

Thionyl chloride (906 mg, 7.61 mmol) was added drop wise to a cold solution of 8-hydroxyquinoline-7-carboxylic acid (1.2 g, 6.34 mmol) in dry DCM (18 mL). The reaction mixture was allowed to warm to RT and was then stirred under nitrogen for 4 h. The reaction mixture was then concentrated to dryness affording the title compound (1.3 g, 6.26 mmol) that was used in the next steps without any further purification.

Provenance & Evidence