HCID 66787439, compound → HCID 9985366, compound

HRID 1025699Notes

Reaction equation

HRID 1025699 reaction equation
Cl.[O:2]=[C:3]([NH:18][CH:19]1[CH:23]([O:24][CH2:25][CH2:26][CH3:27])[CH2:22][NH:21][CH2:20]1)[CH2:4][NH:5][C:6](=[O:17])[C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([C:13]([F:16])([F:15])[F:14])[CH:8]=1.[OH:28][C:29]1([C:36]2[CH:41]=[CH:40][N+:39]([O-:42])=[CH:38][CH:37]=2)[CH2:34][CH2:33][C:32](=O)[CH2:31][CH2:30]1>>[OH:28][C:29]1([C:36]2[CH:41]=[CH:40][N+:39]([O-:42])=[CH:38][CH:37]=2)[CH2:30][CH2:31][CH:32]([N:21]2[CH2:22][C@H:23]([O:24][CH2:25][CH2:26][CH3:27])[C@@H:19]([NH:18][C:3](=[O:2])[CH2:4][NH:5][C:6](=[O:17])[C:7]3[CH:12]=[CH:11][CH:10]=[C:9]([C:13]([F:16])([F:15])[F:14])[CH:8]=3)[CH2:20]2)[CH2:33][CH2:34]1

Participants

3

Reactant 2

HCID 66787439HCID 66787439, compoundHCID 66787603HCID 66787603, compound

Product 1

HCID 9985366HCID 9985366, compound

Procedure

This compound was synthesized from N-(2-oxo-2-{[4-propoxypyrrolidin-3-yl]amino}ethyl)-3-(trifluoromethyl)benzamide hydrochloride and 4-hydroxy-4-(1-oxidopyridin-4-yl)cyclohexanone according to typical reductive animation precedure. MS (m/e): 565 (M+1)+.

Sources & evidence

ORD record
ord-61ff23267dc34947a261738cbc4574ca
Source dataset
uspto-grants-2014_05
Patent number
US08729063B2

Reaction notes

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