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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1025713Generated: October 29, 2026

4-(1-Hydroxy-4-oxocyclohexyl)benzonitrile → 6-(1-Hydroxy-4-oxocyclohexyl)nicotinonitrile

https://huagongshe.com/reaction/1025713

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(1-Hydroxy-4-oxocyclohexyl)benzonitrileHCID 66787229—
Reactant6-(8-Hydroxy-1,4-dioxaspiro[4.5]dec-8-yl)nicotinonitrileHCID 66787727—
Product6-(1-Hydroxy-4-oxocyclohexyl)nicotinonitrileHCID 66788003—

Reaction Steps

The title compound was synthesized from 6-(8-hydroxy-1,4-dioxaspiro[4.5]dec-8-yl)nicotinonitrile using the sane typical deprotection procedure as for 4-(1-hydroxy-4-oxocyclohexyl)benzonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08729063B2
Source datasetuspto-grants-2014_05
ORD IDord-71659a52cb914868ac2a628d3e74363d
Source noteuspto-grants-2014_05